Susan Lindquist
Susan Lee Lindquist, (Yuni 5, an haife ta a shekara ta alif dari tara da alba'in da tara1949A.c -ta mutu a watan Oktoba 27, 2016) wata farfesa ce yar kasar amurka tayi karatu a fannin ilmin halitta a MIT [1] [2] ƙwareriya a fannin ilmin kwayoyin halitta, musamman matsalar nadawa sunadaran [3] a cikin dangin kwayoyin da aka sani da sunadaran zafi-shock, [4] [5] da prions . [6] Lindquist ya kasance memba kuma tsohon darektan Cibiyar Whitehead kuma an ba shi lambar yabo ta Kimiyya ta ƙasa a cikin 2010. [7] [8] [9]
Rayuwar farko da ilimi
gyara sasheAn haifi Lindquist a Chicago, Illinois, zuwa Iver da Eleanor (née Maggio), kuma ya halarci makarantar sakandare ta Maine South a Park Ridge . [10]
Lindquist's father and mother were of Swedish and Italian descent, respectively,[11] and although they expected her to become a housewife,[12] Susan studied microbiology at the University of Illinois as an undergraduate and received her PhD in biology from Harvard University in 1976.[13] She completed a post-doctoral fellowship at the American Cancer Society.
Sana'a
gyara sasheBayan kammala karatun ta a 1976, Lindquist ya koma Jami'ar Chicago don ɗan gajeren lokaci kafin a ɗauke shi aiki a matsayin mamba a Sashen Biology a 1978, [14] ya zama Albert D. Lasker Farfesa na Kimiyyar Kiwon Lafiya tare da kafa. na Sashen Kwayoyin Halitta da Halittu na Halitta a cikin 1980. A Jami'ar Chicago Lindquist ya binciki rawar da sunadaran girgiza zafi ke takawa wajen daidaita martanin salon salula ga matsalolin muhalli. Lindquist ya fara yin amfani da yisti a matsayin tsarin samfuri don nazarin yadda sunadaran girgiza zafin jiki ke daidaita maganganun kwayoyin halitta da nadewar furotin. Don wannan aikin, an sanya Lindquist mai bincike na Cibiyar Kiwon Lafiya ta Howard Hughes a cikin 1988. [14] Bayan yin muhimman sababbin binciken zuwa prions, Lindquist ya koma MIT a cikin 2001 kuma an nada shi a matsayin Daraktan Cibiyar Nazarin Halittu ta Whitehead, ɗaya daga cikin mata na farko a cikin al'umma don jagorantar babbar ƙungiyar bincike mai zaman kanta. [15]
A cikin 2004, Lindquist ya ci gaba da bincike a matsayin Memba na Cibiyar, abokin tarayya na Broad Institute of MIT da Harvard, da kuma memba na David H. Koch Institute for Integrative Cancer Research a MIT. [16]
An ba Lindquist lambar yabo ta Kimiyya ta ƙasa a cikin 2009 (wanda aka gabatar a cikin 2010), don gudummawar bincike don nada furotin. [17]
Lindquist ya gabatar da lacca a cikin ƙasa da kuma na duniya kan batutuwan kimiyya iri-iri. A watan Yuni 2006, ta kasance baƙo na farko a kan "Futures in Biotech" podcast akan hanyar sadarwar TWiT na Leo Laporte . [18] A cikin 2007, ta halarci taron tattalin arzikin duniya a Davos, Switzerland tare da sauran shugabannin MIT. [19]
Lindquist kuma ya haɗu da kamfanoni biyu don fassara bincike zuwa hanyoyin da za a iya amfani da su, FoldRx in da Yumanity Therapeutics a, kamfanoni masu haɓaka magungunan ƙwayoyi don cututtukan ɓarna furotin da amyloidosis. [20] [21]
Manazarta
gyara sashe- ↑ Hopkins, N. (2008). "The 2008 Genetics Society of America Medal". Genetics. 178 (3): 1125–1128. doi:10.1534/genetics.104.017834. PMC 2278094. PMID 18385104
- ↑ "Susan Lindquist". Royal Society. Retrieved October 30, 2016
- ↑ Gitschier, J. (2011). "A Flurry of Folding Problems: An Interview with Susan Lindquist". PLOS Genetics. 7 (5): e1002076. doi:10.1371/journal.pgen.1002076. PMC 3093363. PMID 21589898
- ↑ "Whitehead Institute – Faculty". Whitehead.mit.edu. Retrieved October 30, 2016.
- ↑ "Lindquist Lab | Lindquist Lab at the Whitehead Institute for Biomedical Research | Lindquist Lab". mit.edu. February 10, 2016. Retrieved October 30, 2016.
- ↑ Kain, K. (2008). "Using yeast to understand protein folding diseases: An interview with Susan Lindquist". Disease Models and Mechanisms. 1 (1): 17–19. doi:10.1242/dmm.000810. PMC 2561974. PMID 19048046
- ↑ Lindquist, S. (1986). "The Heat-Shock Response". Annual Review of Biochemistry. 55: 1151–91. doi:10.1146/annurev.bi.55.070186.005443. PMID 2427013. S2CID 42450279
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- ↑ Parsell, D.A.; Lindquist, S. (1993). "The Function of Heat-Shock Proteins in Stress Tolerance: Degradation and Reactivation of Damaged Proteins". Annual Review of Genetics. 27: 437–96. doi:10.1146/annurev.ge.27.120193.002253. PMID 8122909. S2CID 31351089
- ↑ Grimes, William (October 28, 2016). "Susan Lindquist, Scientist Who Made Genetic Discoveries Using Yeast, Dies at 67". The New York Times. ISSN 0362-4331. Retrieved October 30, 2016.
- ↑ "Whitehead Institute – Faculty". mit.edu. Retrieved October 30, 2016.
- ↑ "Susan Lindquist – 2009 National Medal of Science". YouTube. November 29, 2010. Archived from the original on December 11, 2021. Retrieved October 30, 2016
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