Gundumar Assin ta Tsakiya (da aka fi sani da Gundumar Assin Fosu) tana ɗaya daga cikin gundumomi ashirin da biyu a Yankin Tsakiyar Ghana, Ghana. Tun asali yana cikin gundumar Assin mafi girma a lokacin a cikin 1988, har zuwa lokacin da aka raba yankin kudancin gundumar don ƙirƙirar gundumar Assin ta Kudu a ranar 18 ga Fabrairu 2004; Don haka an mayar da ragowar yankin suna zuwa gundumar Assin ta Arewa ta farko, wanda daga baya aka mayar da ita matsayin majalisar gunduma a ranar 29 ga Fabrairu 2008 ta zama gundumar Assin North Municipal. Duk da haka a ranar 15 ga Maris 2018, an raba yankin kudancin gundumar don ƙirƙirar gundumar Assin ta Arewa na yanzu; don haka ragowar sashin an canza masa suna zuwa Assin Central Municipal District. Gundumar tana yankin arewa maso yamma na yankin tsakiya kuma tana da Assin Fosu a matsayin babban birninta.