Tofersen
Tofersen, wanda aka sayar a ƙarƙashin sunan alama Qalsody, magani ne da ake amfani da shi don magance cututtukan cututtuka na amyotrophic (ALS). Musamman ana amfani dashi a cikin mutanen da ke da maye gurbin kwayar halittar superoxide dismutase 1 (SOD1), wanda ke cikin kashi 2% na lokuta. [1] Ana ba da ita ta hanyar allura a cikin kashin baya . [1]
 Tofersen | |
|---|---|
type of chemical entity (en)  | |
| Bayanai | |
| Ƙaramin ɓangare na |
chemical compound (en) |
| Amfani | magani |
| Subject has role (en) |
antisense oligonucleotide (en) |
Abubuwan da ke tattare da illa sun haɗa da gajiya, ciwon haɗin gwiwa, ƙara yawan fararen jini na CSF, da ciwon tsoka. Sauran illa na iya haɗawa da myelitis, ƙara yawan matsa lamba na intracranial, da kuma meningitis aseptic . [1] Yana da maganin antisense oligonucleotide wanda ke rage gwagwala superoxide dismutase 1 samarwa. [1]
An amince da Tofersen don amfani da likita a Amurka a cikin shekarar 2023. Kamar yadda na shekarar 2023 yana kashe kimanin 158,000 USD a kowace shekara a Amurka. Ya sami matsayin magungunan marayu a Turai a cikin shekara ta 2016.