Vofopitant
Vofopitant (GR205171) shi ne mai magani da abubuwa a matsayin wani NK 1 kamar tsoka mai amsa sigina ne antagonist . Yana da tasirin irin na antiemetic kamar yadda yake tare da sauran abokan adawar NK 1 kuma yana nuna ayyukan tashin hankali a cikin dabbobi. Anyi nazarin shi don aikace-aikace kamar jiyya ta phobia ta zamantakewa da rikicewar damuwa bayan tashin hankali, amma bai tabbatar da isasshen tasiri don siyarwa ba.
Vofopitant | |
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type of chemical entity (en) | |
Bayanai | |
Ƙaramin ɓangare na | [[d:Special:EntityPage/Q126610318|N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-2-phenylpiperidin-3-amine]] (en) |
Sinadaran dabara | C₂₁H₂₃F₃N₆O |
Canonical SMILES (en) | COC1=C(C=C(C=C1)N2C(=NN=N2)C(F)(F)F)CNC3CCCNC3C4=CC=CC=C4 |
Isomeric SMILES (en) | COC1=C(C=C(C=C1)N2C(=NN=N2)C(F)(F)F)CN[C@H]3CCCN[C@H]3C4=CC=CC=C4 |
Ta jiki ma'amala da | Tachykinin receptor 1 (en) |
Subject has role (en) | antiemetic (en) da NK1 receptor antagonists (en) |
Duba kuma
gyara sashe- NK 1 antagonist mai karɓa