Wikipedia

Kwayar Cutar Corynebacterium diphtheriae

kwayar cutar Corynebacterium diphtheriae sitace kwayoyin cutar da ke haifar da cutar diphtheria . [1] An kuma san ta da Klebs-Löffler bacillus, saboda an gano shi a cikin 1884 ta masu binciken kwayoyin cutar na Jamus Edwin Klebs (1834-1912) da Friedrich Löffler (1852-1915). [2] Kwayoyin yawanci ba su da lahani sai dai idan sukayi tarayya da kwayar cutar bacteriophage mai dauke da kwayar halittar da ke haifar da guba . [3] Wannan guba yana haifar da cutar. [4]Diphtheria tana faruwa ne ta hanyar mannewa da kutsawa daga cikin kwayoyin cuta zuwa cikin sassan jikin mucosal, da farko yana shafar hanyoyin numfashi da sakin dafi na gaba. [4]dafin yana da tasiri mai tasiri akan raunuka na fata, da kuma metastatic, tasirin proteolytic akan sauran tsarin gabobin a cikin jiki masu tsanani. [5] Asalin babban dalilin mace-macen yara, diphtheria ya kusan kawar da shi saboda tsananin gudanar da allurar diphtheria a cikin 1910s.[6]

Kwayar Cutar Corynebacterium diphtheriae
Scientific classification
KingdomBacillati (en) Bacillati
PhylumActinomycetota (mul) Actinomycetota
ClassActinomycetes (mul) Actinomycetes
OrderMycobacteriales (mul) Mycobacteriales
DangiCorynebacteriaceae (mul) Corynebacteriaceae
GenusCorynebacterium (mul) Corynebacterium
jinsi Corynebacterium diphtheriae
,
General information
Rashin lafiya diphtheria (en) Fassara, diphtheritic peritonitis (en) Fassara, cutaneous diphtheria (en) Fassara da pseudomembranous conjunctivitis (en) Fassara
Gram stain gram-positive bacteria (en) Fassara

Diphtheria baya yaduwa akai-akai saboda haɓakar rigakafinta, DTaP. Ko da yake ana ci gaba da samun barkewar cutar diphtheria, wannan sau da yawa a cikin ƙasashe masu tasowa inda yawancin jama'a ba a yi musu allurar rigakafi ba. [7]

Rabe- rabe

gyara sashe

An gane nau'o'i hudu: C. d. matsi, C.d. intermedius, C.d. gravis, da C.d. belfanti . Daban-daban nau'ikan nau'ikan nau'ikan guda huɗu sun bambanta kaɗan kaɗan a cikin tsarin halittarsu na mulkin mallaka da kaddarorin sinadarai, kamar ikon sarrafa wasu abubuwan gina jiki. Duk yana iya zama mai guba (sabili da haka yana haifar da diphtheria) ko ba mai guba ba.

Rubutun nau'i-nau'i ya ƙunshi kwatanta nau'in kwayoyin cuta da rarraba su zuwa nau'i-nau'i. [8] Rubutun juzu'i shima yana taimakawa wajen gano asalin fashewar wasu kwayoyin cuta. Duk da haka, idan ya zo ga subtyping na C. diphtheriae, babu wani abu mai yawa mai amfani ko daidaitaccen rarrabuwa saboda rashin wadataccen albarkatun jama'a don gano nau'i don haka gano asalin fashewa. [9]

manazarta

gyara sashe
  1. ↑ Hoskisson PA (June 2018). "Microbe Profile: Corynebacterium diphtheriae - an old foe always ready to seize opportunity". Microbiology. 164 (6): 865–867. doi:10.1099/mic.0.000627
  2. ↑ Barksdale L (December 1970). "Corynebacterium diphtheriae and its relatives". Bacteriological Reviews. 34 (4): 378–422. doi:10.1128/br.34.4.378-422.1970. PMC 378364. PMID 4322195
  3. ↑ Ott L, Möller J, Burkovski A (March 2022). "Interactions between the Re-Emerging Pathogen Corynebacterium diphtheriae and Host Cells". International Journal of Molecular Sciences. 23 (6): 3298. doi:10.3390/ijms23063298
  4. ↑ 4.0 4.1 Muthuirulandi Sethuvel DP, Subramanian N, Pragasam AK, Inbanathan FY, Gupta P, Johnson J, et al. (2019). "Insights to the diphtheria toxin encoding prophages amongst clinical isolates of Corynebacterium diphtheriae from India". Indian Journal of Medical Microbiology. 37 (3): 423–425. doi:10.4103/ijmm.IJMM_19_469. PMID 32003344
  5. ↑ Muthuirulandi Sethuvel DP, Subramanian N, Pragasam AK, Inbanathan FY, Gupta P, Johnson J, et al. (2019). "Insights to the diphtheria toxin encoding prophages amongst clinical isolates of Corynebacterium diphtheriae from India". Indian Journal of Medical Microbiology. 37 (3): 423–425. doi:10.4103/ijmm.IJMM_19_469. PMID 32003344
  6. ↑ https://pubmed.ncbi.nlm.nih.gov/10657202
  7. ↑ Clarke KE, MacNeil A, Hadler S, Scott C, Tiwari TS, Cherian T (October 2019). "Global Epidemiology of Diphtheria, 2000-20171". Emerging Infectious Diseases. 25 (10): 1834–1842. doi:10.3201/eid2510.190271. PMC 6759252. PMID 31538559
  8. ↑ "Diphtheria - Symptoms and causes". Mayo Clinic. Retrieved 2022-11-17.
  9. ↑ Empty citation (help)
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