English: "Global hypoxia-induced surge of high-frequency oscillations in the brain of dying patients. (A) Absolute power of left anterior-mid temporal lobe (T3) before (S1) and after (S2 to S11) the withdrawal of ventilatory support in Pt1. The power spectrogram was presented in two separate parts (Bottom: 0 to 30 Hz; Top: 30 to 256 Hz) to highlight potentially unique features in slow waves (delta-beta). (B) Spatial and temporal dynamics of absolute power at baseline (S1) and at near-death stages (S2 to S11) in six frequency bands: delta (0 to 4 Hz), theta (4 to 8 Hz), alpha (8 to 13 Hz), beta (13 to 25 Hz), gamma1 (25 to 55 Hz), and gamma2 (80 to 150 Hz) in Pt1. (C) Temporal changes of beta, gamma1, and gamma2 power in 16 EEG loci (excluding the midline areas covered by Fz, Cz, and Pz electrodes) in Pt1. (D) Gamma power in four cortical regions (F7, F8, C3, and C4) in the four patients at baseline (S1) and after the termination of breathing support in S2." "In the left anterior-mid temporal lobe (T3) of Pt1, gamma power (>25 Hz) showed a marked surge at near-death, increasing within seconds after ventilator removal in S2 and remaining visually detectable until the early period in S10 (Fig. 1A). Elevation of absolute EEG power in beta (15 to 25 Hz), gamma1 (25 to 55 Hz) and gamma2 (80 to 150 Hz) bands across the dying brain was evident in S2 in frontal and central areas for both Pt1 (Fig. 1B) and Pt3 (SI Appendix, Fig. S2b), while they were undetectable in Pt2 and Pt4 (SI Appendix, Fig. S2 A and C). Right (in S4) and left (in S7, S8) temporal lobes showed further increase of gamma power in the later dying stages in Pt1 (Fig. 1B). Quantification of temporal distribution of beta, gamma1, and gamma2 power across all monitored electrodes (Fig. 1C) confirmed the visual inspection (Fig. 1B) for Pt1: somatosensory cortices (SSCs; C3 and C4) as well as the right dorsolateral prefrontal cortex (DLPFC; F4), nearly silent in S1, showed a marked surge in gamma power in S2. The rise in gamma power was also seen in the left and right ventrolateral prefrontal cortex (VLPFC; F7, F8) as well as in the SSCs of both Pt1 (Fig. 1 B–D) and Pt3 (Fig. 1D and SI Appendix, Fig. S2B) with the increase ranging from 2- to 391-fold in S2 compared to S1 (Fig. 1D). Pt2 and Pt4 showed absence of gamma power increase at near-death (Fig. 1D and SI Appendix, Fig. S2 A–C). Therefore, we focused all our subsequent analyses on Pt1 and Pt3."