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English: Neuropilin-2 (Nrp2) expression in normal breast and breast carcinoma tissue. (A) Nrp2 staining was observed in blood or lymph vessels. There was no staining in normal breast epithelium. (×100). (B) In cancer tissue, staining of the Nrp2 protein was identified not only in the vascular endothelial cells, but also in the cytoplasm of cancer cells. Almost all invasive cells were immunopositive for Nrp2. (×200). (C-D) Co-localized expression of Nrp2 (C) and CXCR4 (D) using serial sections of breast carcinoma tissue. (×100). Yasuoka et al. BMC Cancer 2009 9:220 doi:10.1186/1471-2407-9-220
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Masomi Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression
Marubucin Hironao Yasuoka1 , Rieko Kodama1 , Masahiko Tsujimoto2 , Katsuhide Yoshidome3 , Hiroki Akamatsu3 , Masaaki Nakahara3 , Michiya Inagaki1 , Tokio Sanke1 and Yasushi Nakamura1
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© 2009 Yasuoka et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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na yanzu16:42, 17 ga Augusta, 2009Wadar sufa ta zubin 16:42, 17 ga Augusta, 20091,200 × 900 (498 KB)CopperKettle{{Information |Description={{en|1=Neuropilin-2 (Nrp2) expression in normal breast and breast carcinoma tissue. (A) Nrp2 staining was observed in blood or lymph vessels. There was no staining in normal breast epithelium. (×100). (B) In cancer tissue, stai

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