Allurar rigakafin annoba
vaccine type (en) Fassara
Bayanai
Ƙaramin ɓangare na bacterial vaccine (en) Fassara
Vaccine for (en) Fassara plague (en) Fassara da Yersinia pestis (mul) Fassara

Alurar rigakafin annoba Ta kasance wani maganin da ake amfani dashi akan Yersinia pestis domin hana kamuwa ko warkarwa daga annoba .[1] An yi amfani da allurar rigakafin ƙwayoyin cuta da ba a kunna ba tun daga 1890 amma ba su da tasiri a kan cutar ta huhu, domin haka an ɓullo da raye-rayen da ba a yi amfani da su ba, da kuma allurar rigakafi na furotin da aka sake haɗawa don hana cutar. [2]

rigakafin annoba

gyara sashe

Masanin ilimin kwayoyin cuta Waldemar Haffkine ne ya samar da rigakafin annoba ta farko a cikin 1897. [3] [4] Ya gwada maganin a kansa don tabbatar da cewa maganin ba shi da lafiya. [4] [5] Daga baya, Haffkine ya gudanar da wani gagarumin shirin inoculation a Birtaniya Indiya, kuma an kiyasta cewa an aika da allurai miliyan 26 na maganin rigakafin cutar Haffkine daga Bombay tsakanin 1897 zuwa 1925, wanda ya rage yawan mace-mace da 50% -85%. [6]

Ana amfani da rigakafin annoba don shigar da takamaiman rigakafi mai aiki a cikin kwayoyin halitta mai saurin kamuwa da cutar ta hanyar sarrafa kayan antigenic ( alurar rigakafi ) ta hanyoyi daban-daban ga mutanen da ke cikin haɗarin kamuwa da kowane nau'in annoba na asibiti. Ana kiran wannan hanyar da rigakafin annoba . Akwai kwakkwarar shaida kan ingancin gudanar da wasu alluran rigakafin annoba wajen hanawa ko inganta tasirin nau'ikan kamuwa da cuta iri-iri ta Yersinia pestis . Har ila yau, rigakafin annoba ya ƙunshi haifar da yanayi na musamman na rigakafi ga annoba a cikin kwayoyin halitta mai sauƙi bayan gudanar da kwayar cutar annoba ko annoba ta rigakafi a cikin mutanen da ke da hadarin kamuwa da cutar nan da nan. [7]

Wani bita na tsari na Cochrane Collaboration ya sami wani bincike na isassun ingancin da za a haɗa a cikin bita, don haka ba su iya yin wata sanarwa game da ingancin rigakafin zamani ba. [8]

Manazarta

gyara sashe
  1. Samfuri:MeshName
  2. Bubeck SS, Dube PH (September 2006). "Yersinia pestis CO92ΔyopH Is a Potent Live, Attenuated Plague Vaccine". Clin. Vaccine Immunol. 14 (9): 1235–8. doi:10.1128/CVI.00137-07. PMC 2043315. PMID 17652523.
  3. "Waldemar Haffkine: The vaccine pioneer the world forgot". BBC News (in Turanci). 2020-12-11. Retrieved 2021-01-20.
  4. 4.0 4.1 "WALDEMAR MORDECAI HAFFKINE". Haffkine Institute. Archived from the original on 2015-09-24. Retrieved 2021-01-20.
  5. Yang, Wei (July 2010). "[The pioneer of cholera vaccine and plague vaccine-Haffkine]". Zhonghua Yi Shi Za Zhi (Beijing, China: 1980). 40 (4): 243–246. ISSN 0255-7053. PMID 21122347.
  6. Hawgood, Barbara J. (February 2007). "Waldemar Mordecai Haffkine, CIE (1860-1930): prophylactic vaccination against cholera and bubonic plague in British India". Journal of Medical Biography. 15 (1): 9–19. doi:10.1258/j.jmb.2007.05-59. ISSN 0967-7720. PMID 17356724. S2CID 42075270.
  7. "WHO | Zoonotic Infections". www.who.int. Archived from the original on 22 March 2006. Retrieved 15 January 2022.
  8. Jefferson T, Demicheli V, Pratt M (2000). "Vaccines for preventing plague". Cochrane Database Syst Rev. 1998 (2): CD000976. doi:10.1002/14651858.CD000976. PMC 6532692. PMID 10796565.